An unusual localization a mebazaa 1, s trabelsi 1, m denguezli 1, b sriha 2, c belajouza 1, r nouira 1 dermatology online journal 12 1. They are typically found on the eyelids, but may also develop in other parts of the body with sebaceous ducts such as in the umbilicus, chest, armpits, breasts, genitals or vulva. Chondroid syringoma is also known as mixed tumour of the skin. Syringoma definition of syringoma by medical dictionary. Chondroid syringoma cs is a benign cutaneous adnexal tumor with epithelial and stromal components.
Case report facial localization of malignant chondroid syringoma. Pathology of chondroid syringoma mixed tumour of the skin. Chondroid syringoma is a cutaneous mixed tumor of salivaryglandtype usually located in the head and neck region. For chondroid syringoma, total excision is recommended, 2. Nov 14, 2016 if you have problems viewing pdf files, download the latest version of adobe reader. Epithelial components derived from folliculosebaceousapocrine germ are evident in apocrine but not in eccrine cs. The tumour is composed of both epithelial and mesenchymal components. First described by hirsch and helwig in 1961, chondroid syringomas css are rare, benign tumors of the skin arising from the eccrine sweat glands with tumor. The name syringoma is derived from the greek word syrinx, which means pipe or tube. Histopathologic and immunohistochemical examination showed a chondroid syringoma, an uncommon benign neoplasm of possible eccrine sweat gland origin, which occurs generally in the head and neck skin. It is generally localized in the head and neck region and rarely in the extremities. For language access assistance, contact the ncats public information officer.
Department of pathology, faculty of medicine, dumlupinar university kutahya, turkey. There is no systemic involvement and no associated conditions or disease states. In contrast to the benign counterpart, which is common in the head and neck region, the malignant variety occurs predominantly on the trunk and extremities. Chondroid syringoma is a benign tumor but incomplete excision can undergo malignant transformation. An 81yearold man underwent excisional biopsy of a big cylindric painless mass of the right lower eyelid, which had been present for over 23 years. We report a case of a 41yearold woman with orbital cs. Because of the unremarkable clinical symptomatology of this rare tumor, the diagnosis is exclusively made retrospectively based on histological confirmation of the surgically. Article benign chondroid syringoma applied radiology. Histopathologic and immunohistochemical examination showed a chondroid syringoma, an uncommon benign neoplasm of possible eccrine sweat gland.
Apr 01, 2009 benign chondroid syringoma mixed tumor discussion a chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. The chondroid syringoma is usually a smallsized skin tumor, frequently on the head and neck. All the cases had a myxoid matrix and most also had a chondroid one. We report a case of a preauricular nodule at presentation and highlight the importance of differentiating a chondroid syringoma from a pleomorphic adenoma. This tumor developed slowly over 8 years causing indolor, no axil, exophtalmos of the left eye. A chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. It is also called as mixed tumor of skin because of the presence of. Histopathology a cornerstone tool in diagnosis find, read. Department of pathology, hokkaido university school of medicine, kita. Syringoma is a tumor in the sweat ducts that are commonly harmless. These lesions present as nondescript dermal nodules which grow slowly.
They most often arise on the skin of the head and neck. Chondroid syringoma mixed tumor of the skin a clinicopathological study of cases. Facial localization of malignant chondroid syringoma. Chondroid syringoma, or pleomorphic adenoma of the skin, is a rare, benign skin adnexal tumor. Chondroid syringoma chondroid syringoma is a rare benign skin adnexal tumor of eccrineapocrine origin affecting commonly the head and neck region. Outcomesresolutions the prognosis for chondroid syringoma is generally excellent with appropriate treatment, since it is a benign tumor. Chondroid syringoma is a cutaneous sweat gland tumor. It includes dermatologic cancer, which can be deadly. Mar 27, 2019 syringoma is a benign adnexal neoplasm formed by welldifferentiated ductal elements. Department of radiation, oncology, gandhi medical college, bhopal, madhya pradesh, india.
Chondroid syringoma is a rare benign skin adnexal tumor of eccrineapocrine origin affecting commonly the head and neck region. This case is being reported for its rarity this is the 28 th case in literature involving ocular adnexa, its occurrence in a young patient and the need to keep this rare entity as a differential diagnosis of eyelid tumors. Jul 20, 2014 chondroid syringoma is also known as mixed tumour of the skin. Rapidly growing chondroid syringoma of the external auditory canal. Computed tomography demonstrated an isodense intraorbital tumor with. Giant chondroid syringoma of the lower eyelid ncbi nih. Chondroid syringoma of the scrotum with mix inflammatory.
Syringoma is a benign adnexal tumour originating from the intraepidermal portion of the eccrine duct. Chondroid syringoma cs of the orbit is an extremely rare benign. Five of the eight cases were apocrine, one of them with follicular and sebaceous differentiation. Currently, there are no known methods to prevent chondroid syringoma occurrence. Aug 12, 2018 how can chondroid syringoma be prevented. The pathologic diagnoses were all consistent with cutaneous benign mixed tumor chondroid syringoma, pleomorphic adenoma. Case report facial localization of malignant chondroid. In the few cases studied, radiography of malignant chondroid syringoma tends to show higher signal intensity than muscle on proton sequence, and high signal enhancement with focal intermediate signal on stir short t1 inversion australas radiol 2001.
Chondroid syringoma or mixed skin tumour is a rare, benign skin adnexal tumour which typically occurs in the head and neck region of middleaged patients. Clear cell syringoma are commonly associated with diabetes mellitus. On histopathologic examination, the tumors were biphasic, with an epithelial component exhibiting apocrine or hair follicle differentiation and a myxoid, adipocytic, chondroid, andor fibrous stroma. Chondroid syringoma is a rare benign skin adnexal tumor, the cytological features of which have been published very rarely in the literature. Mar 31, 2014 discussion chondroid syringoma also known as mixed tumour of the skin benign adnexal tumour with an unknownaetiopathogenesis. Clinicians diagnosing and treating diseases of the head and neck should be aware of these tumors.
A rare case report deniztural, 1 fatihselcukbiricik, 1 feraygunver, 2 abdulkadirkar jgmaz, 1 andsuheylaserdengecti 1 division of medical oncology, department of internal medicine, cerrahpasa medical faculty, istanbul university, tr istanbul, turkey. Chondroid syringoma is a benign mixed tumor characterized by sweat gland elements in a cartilaginous stroma. Pilosebaceous differentiation in chondroid syringomasalama et al. Pdf chondroid syringoma in a child onder sahin and. A mucoid aspirate, abundant chondromyxoid matrix material, and epithelial components were suggested as diagnostic criteria. Below are the links to the authors original submitted files for images. The chondroid syringoma is an extremely rare skin tumor most commonly found in the area of the head and neck region. Apr, 2018 chondroid syringoma or mixed skin tumour is a rare, benign skin adnexal tumour which typically occurs in the head and neck region of middleaged patients. A well circumscribed but unencapsulated, multilobulated mass centered in deep dermis or subcutaneous fat, with a prominent chondroid or myxoid stroma enveloping benign bland appearing epithelial and myoepithelial cells that form secondary structures. Apocrine mixed tumour is also known as apocrine chondroid syringoma.
Collectively, dermatologic cancers are the most common form of cancer. Chondroid syringoma definition of chondroid syringoma by. Chondroid syringomas cs are rare benign mixed tumours that exhibit both epithelial and mesenchymal components, originating from the sweat glands 1. The dermatoscopy does not seem to supply any specific trait to this lesion. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. To the best of our knowledege, this is the second case reported in the english literature. Due to their rarity, they are often clinically misdiagnosed and with the diagnosis only confirmed on histological examination. Pdf on jan 1, 2016, kanathur shilpa and others published chondroid syringoma. It is usually exhibited as a slowly growing intradermal or subcutaneous nodule, typically located in the head and neck region.
Syringoma treatment, removal, pictures, causes, surgery. Dermal chondroid syringoma diagnostic histopathology. Malignant chondroid syringoma mcs is a rare tumor, of the sweat gland. These lesions are common in patients with down syndrome. They typically comprise sweat gland elements within a prominent cartilagelike stroma. Chondroid syringoma cs of the orbit is an extremely rare benign neoplasm. Its rarity, potential for malignancy, and frequent misdiagnosis for other more. This article deals with dermatologic neoplasms, also known as skin tumours. Recurrent malignant chondroid syringoma of the foot. An 84yearold man presented with an enlarging bluish, painless subcutaneous nodule on the glabella. Sweat gland tumors are uncommon, and yet the chondroid syringoma mixed tumor of the skin appears most frequently on the faces of adults. Cutaneous benign mixed tumor chondroid syringoma of the ey. Despite its relative rarity, a benign and malignant variant have been described.
Rarely, a chondroid syringoma of many years duration suddenly undergoes malignant changes with widespread metastasis. Syringoma genetic and rare diseases information center. Chondroid syringoma mixed tumor of the skin kunikane. Chondroid syringoma is a benign growth, with little proliferative capacity. Chondroid syringoma cs is a rarely seen benign tumor rooted in the epithelial and mesenchymal cells of the skin. Malignant chondroid syringoma agrawal 1998 the journal.
Malignant chondroid syringoma is a mixed cutaneous tumor, with epithelial and mesenchymal components, which compromises principally the trunk and extremities. Chondroid syringoma mix inflammatory infiltration scrotum. The term syringoma is derived from the word syrinx, meaning pipe or tube. A female presented with a subcutaneous swelling on the scalp with repeated recurrence and positive regional lymph nodes. Ultrasonography shows well encapsulated, hyperechoic mass with radiating, hypoechoic septae. We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services.
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